
Xanthurenic Acid
CAS No. 59-00-7
Xanthurenic Acid ( NSC 401570 | Xanthurenate )
产品货号. M15182 CAS No. 59-00-7
黄尿酸或黄尿酸盐是一种化学物质,可诱导恶性疟原虫配子发生,恶性疟原虫是引起疟疾的寄生虫。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
100MG | ¥340 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Xanthurenic Acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述黄尿酸或黄尿酸盐是一种化学物质,可诱导恶性疟原虫配子发生,恶性疟原虫是引起疟疾的寄生虫。
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产品描述Xanthurenic acid, or xanthurenate, is a chemical shown to induce gametogenesis of Plasmodium falciparum, the parasite that causes malaria. It is found in the gut of the Anopheles mosquito. Xanthurenic acid is a metabolic intermediate that accumulates and is excreted by pyridoxine (vitamin B6) deficient animals after the ingestion of tryptophan.
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体外实验——
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体内实验Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. The inhibition of Xanthurenic acid (XA) on sensory can be found when applied iontophoretically and i.v., is similar to that of other Group II mGlu receptor agonists in reducing inhibition evoked in the VB from the thalamic reticular nucleus upon physiological sensory stimulation. Furthermore, it is postulated that Xanthurenic acid may be the first potential endogenous allosteric agonist for the mGlu receptors. As the Group II receptors and kynurenine metabolism pathway have both been heavily implicated in the pathophysiology of schizophrenia, Xanthurenic acid could play a pivotal role in antipsychotic research as this potential endocoid represents both a convergence within these two biological parameters and a novel class of Group II mGlu receptor ligand.
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同义词NSC 401570 | Xanthurenate
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number59-00-7
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分子量205.17
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分子式C10H7NO4
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESOC(=O)C1=CC(=O)C2=C(N1)C(O)=CC=C2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Haruki H, et al. J Biol Chem. 2015 Nov 12. pii: jbc.C115.680488.
产品手册




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